Images in Haematology
Systemic mastocytosis simulating osseous metastatic disease
Georgia Metzgeroth, Dietmar Dinter, Philipp Erben, Paul La Rosée, Rüdiger Hehlmann, Jan Hastka
p. 1
Porphyria cutanea tarda complicating transfusion-dependent myelodysplastic syndrome
J. M. R. Goulding, G. Purohit, A. Borg, P. Rose, B. C. Gee
p.2
Reviews
PGK deficiency
Ernest Beutler
p.3
Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors
Birgit M. Reipert, Pauline M. W. van den Helden, Hans-Peter Schwarz, Christina Hausl
p.12
Guideline
Recommendations from the British Committee for Standards in Haematology and National Patient Safety Agency
T. P. Baglin, D. Cousins, D. M. Keeling, D. J. Perry, H. G. Watson
p.26
Haematological Malignancy
Are clonal T-cell large granular lymphocytes to blame for unexplained haematological abnormalities?
Indu Sabnani, Patricia Tsang
p.30
Profiling of apoptosis genes allows for clinical stratification of primary nodal diffuse large B-cell lymphomas
J. J. F. Muris, B. Ylstra, S. A. G. M. Cillessen, G. J. Ossenkoppele, J. C. Kluin-Nelemans, P. P. Eijk, B. Nota, M. Tijssen, W. P. H. de Boer, M. van de Wiel, P. R. L. A. van den Ijssel, P. Jansen, P. C. de Bruin, J. H. J. M. van Krieken, G. A. Meijer, C. J. L. M. Meijer, J. J. Oudejans
p.38
Identification of transcripts modulated by ETV6 expression
Gino Boily, Josiane Larose, Sylvie Langlois, Daniel Sinnett
p.48
Due to low infection rates no routine anti-infective prophylaxis is required in younger patients with chronic lymphocytic leukaemia during fludarabine-based first line therapy
Barbara F. Eichhorst, Raymonde Busch, Carmen Schweighofer, Clemens M. Wendtner, Berthold Emmerich, Michael Hallek, the German CLL Study Group (GCLLSG)
p.63
Trinucleotide repeat dynamic mutation identifying susceptibility in familial and sporadic chronic lymphocytic leukaemia
Rebecca L. Auer, Guillaume Dighiero, Lynn R. Goldin, Denise Syndercombe-Court, Christopher Jones, Suzanne McElwaine, Adrian C. Newland, Christopher D. Fegan, Neil Caporaso, Finbarr E. Cotter
p.73
6q deletion in Waldenström macroglobulinemia is associated with features of adverse prognosis
E. M. Ocio, R. F. J. Schop, B. Gonzalez, S. A. Van Wier, J. M. Hernandez-Rivas, N. C. Gutierrez, R. Garcia-Sanz, M. J. Moro, C. Aguilera, J. Hernandez, R. Xu, P. R. Greipp, A. Dispenzieri, S. M. Jalal, M. Q. Lacy, N. Gonzalez-Paz, M. A. Gertz, J. F. San Miguel, R. Fonseca
p.80
Case–control study of multidrug resistance phenotype and response to induction treatment including or not fludarabine in newly diagnosed acute myeloid leukaemia patients
Michele Malagola, Daniela Damiani, Giovanni Martinelli, Angela Michelutti, Bruno Cesana, Antonio De Vivo, Pier Paolo Piccaluga, Emanuela Ottaviani, Anna Candoni, Antonella Geromin, Mario Tiribelli, Renato Fanin, Nicoletta Testoni, Francesco Lauria, Monica Bocchia, Marco Gobbi, Ivana Pierri, Alfonso Zaccaria, Eliana Zuffa, Patrizio Mazza, Giancarla Priccolo, Luigi Gugliotta, Alessandro Bonini, Giuseppe Visani, Cristina Skert, Cesare Bergonzi, Aldo Maria Roccaro, Carla Filí, Michele Baccarani, Domenico Russo
p.87
Various distinctive cytogenetic abnormalities in patients with acute myeloid leukaemia aged 60 years and older express adverse prognostic value: results from a prospective clinical trial
Bronno van der Holt, Dimitri A. Breems, H. Berna Beverloo, Eva van den Berg, Alan K. Burnett, Pieter Sonneveld, Bob Löwenberg
p.96
Bortezomib disrupts tumour–dendritic cell interactions in myeloma and lymphoma: therapeutic implications
Anjli Kukreja, Aisha Hutchinson, Amitabha Mazumder, David Vesole, Revathi Angitapalli, Sundar Jagannath, Owen A. O'Connor, Madhav V. Dhodapkar
p.106
Combination chemotherapy followed by autologous stem cell transplant for enteropathy-associated T cell lymphoma
Mark J. Bishton, Andrew P. Haynes
p.111
Functional class switch recombination may occur 'in vivo' in Waldenström macroglobulinaemia
Patricia Martín-Jiménez, Ramón García-Sanz, María E. Sarasquete, Enrique Ocio, José J. Pérez, Marcos González, Jesús F. San Miguel
p.114
Transplantation
Capture and generation of adenovirus specific T cells for adoptive immunotherapy
Ilenia Chatziandreou, Kimberly C. Gilmour, Anne-Marie McNicol, Maurizio Costabile, Joanna Sinclair, David Cubitt, John D. M. Campbell, Christine Kinnon, Waseem Qasim, H. Bobby Gaspar
p. 117
Reduced-intensity conditioning followed by T-cell depleted allogeneic stem cell transplantation for patients with chronic myeloid leukaemia and minimal residual disease at the time of transplant: high risk of molecular relapse
Mark Ringhoffer, Stephanie von Harsdorf, Michael Schmitt, Markus Wiesneth, Thorsten Zenz, Stephan Stilgenbauer, Jochen Greiner, Konstanze Döhner, Martin Marx, Hartmut Döhner, Donald Bunjes
p. 127
Platelets, Haemostasis and Thrombosis
Decreased anticoagulant response to tissue factor pathway inhibitor type 1 in plasmas from patients with lupus anticoagulants
Sigurd Liestøl, Per Morten Sandset, Eva Marie Jacobsen, Marie-Christine Mowinckel, Finn Wisløff
p.131
In vitro kinetics of factor VIII activity in patients with mild haemophilia A and a discrepancy between one-stage and two-stage factor VIII assay results
Susan E. Rodgers, Elizabeth M. Duncan, Denise M. Barbulescu, Diana M. Quinn, John V. Lloyd
p. 138
An evaluation of ciclosporin and corticosteroids individually as adjuncts to plasma exchange in the treatment of thrombotic thrombocytopenic purpura
Spero R. Cataland, Ming Jin, Amy K. Ferketich, Melanie S. Kennedy, Eric H. Kraut, James N. George, Haifeng M. Wu
p. 146
Red Cells and Iron
Genomic organisation and regulation of murine alpha haemoglobin stabilising protein by erythroid Kruppel-like factor
Janelle R. Keys, Michael R. Tallack, Denise J. Hodge, Simon O. Cridland, Rakesh David, Andrew C. Perkins
150
A novel beta-delta globin gene fusion, anti-Lepore Hong Kong, leads to overexpression of delta globin chain and a mild thalassaemia intermedia phenotype when co-inherited with ß0-thalassaemia
Chi-Chiu So, Amy Y. Y. Chan, Stella T. Y. Tsang, Anselm C. W. Lee, Wing-Yan Au, Edmond S. K. Ma, Li-Chong Chan
p. 158
Correspondence
Cyclooxygenase-2 (COX-2) in multiple myeloma: prognostic factor or therapeutic target?
Roger G. Owen, Im Fan, Sheila J. M. O'Connor, Rebecca A. Rollett, J. Anthony Child, Faith E. Davies, Andy C. Rawstron
p. 163
Cyclooxygenase-2 in multiple myeloma: prognostic factor or therapeutic target? – Response to Owen et al
R. E. Kast
p.165
Transmission of a follicular lymphoma by allogeneic bone marrow transplantation – evidence to support the existence of lymphoma progenitor cells
Jason Hart, A. Robert Turner, Loree Larratt, James Russell, Bevin Franko, Christine Frantz, Teresa Paonessa, Adnan Mansoor, Raymond Lai
p. 166
Molecular characterisation of pyruvate kinase deficiency – concerns about the description of mutant PKLR alleles
Richard van Wijk, Gert Rijksen, Wouter W. van Solinge
p. 167
Molecular characterisation of pyruvate kinase deficiency – concerns about the description of mutant PKLR alleles – response to van Wijk et al.
Serge Pissard, Henri Wajcman
p.169
Germline mutation identified after amplification of nuclear DNA from citrated plasma
Jeff Hewitt, Ann Y.K. Wong, Louis D. Wadsworth, Ross T.A. MacGillivray
p.171
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